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Research Articles

  1. Cervenak J, Kurrle R, Kacskovics I. Accelerating antibody discovery using transgenic animals overexpressing the neonatal Fc receptor as a result of augmented humoral immunity. Immunol Rev. 2015 Nov;268(1):269-87. doi: 10.1111/imr.12364. Review. (PubMed)
  2. Schneider Z, Jani PK, Szikora B, Végh A, Kövesdi D, Iliás A, Cervenak J, Balogh P, Kurucz I, Kacskovics I. Overexpression of Bovine FcRn in Mice Enhances T-Dependent Immune Responses by Amplifying T Helper Cell Frequency and Germinal Center Enlargement in the Spleen. Front Immunol. 2015 Jul 20;6:357. doi: 10.3389/fimmu.2015.00357. (PubMed)
  3. Dudok B, Barna L, Ledri M, Szabo SI, Szabadits E, Pinter B, Woodhams SG, Henstridge CM, Balla GY, Nyilas R, Varga C, Lee S-H, Matolcsi M, Cervenak J, Kacskovics I, Watanabe M, Sagheddu C, Melis M, Pistis M, Soltesz I, Katona I. 2014. Cell-specific STORM super-resolution imaging reveals nanoscale organization of cannabinoid signaling. Nat Neurosci 2014 Dec 8. doi: 10.1038/nn.3892.(PubMed)
  4. Baranyi M, Cervenak J, Bender B, Kacskovics I. Transgenic Rabbits That Overexpress the Neonatal Fc Receptor (FcRn) Generate Higher Quantities and Improved Qualities of Anti-Thymocyte Globulin (ATG). PLoS One 2013; 8:e76839. (PubMed)
  5. Cervenak J, Doleschall M, Bender B, Mayer B, Schneider Z, Doleschall Z, et al. NF-κB induces overexpression of bovine FcRn: a novel mechanism that further contributes to the enhanced immune response in genetically modified animals carrying extra copies of FcRn. mAbs 2013; 5:858 - 69. (PubMed)
  6. Vegh. A, Farkas, A, Kövesdi. D, Papp. K, Cervenak. J, Schneider. Z, Bender. B, Hiripi. L, László. G, Prechl. G, Matkó. J and Kacskovics, I. (2012). FcRn overexpression in transgenic mice results in augmented APC activity and robust immune response with increased diversity of induced antibodies. PLoS One. 2012;7(4):e36286. PubMed
  7. Duranthon V, Beaujean N, Brunner M, Odening KE, Santos AN, Kacskovics I, Hiripi L, Weinstein EJ, Bosze Z (2012) On the emerging role of rabbit as human disease model and the instrumental role of novel transgenic tools. Transgenic Res. 2012 Aug;21(4):699-713. PubMed
  8. Vegh, A., Cervenak, J., Jankovics, I., and Kacskovics, I. (2011). FcRn overexpression in mice results in potent humoral response against weakly immunogenic antigen. mAbs. March 1; 3(2):173-80. PubMed
  9. Cervenak, J., Bender, B., Schneider, Z., Magna, M., Carstea, B.V., Liliom, K., Erdei, A., Bosze, Z., and Kacskovics, I. (2011). Neonatal FcR overexpression boosts humoral immune response in transgenic mice. Journal of Immunology, 186, 959-968 PubMed
  10. Kacskovics I, Cervenak J, Erdei A, Goldsby RA, Butler JE (2011) Recent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies. mAbs 3: 431-439. PubMed
  11. Lemos APC, Cervenak J, Bender B, Hoffmann O, Baranyi M, Kerekes A, Farkas A, Bosze Z, Hiripi L, Kacskovics I (2011) Characterization of the rabbit neonatal Fc receptor (FcRn) and analyzing the immunophenotype of the transgenic rabbits that overexpress FcRn. PLoS One; 7(1):e28869. PubMed
  12. Schneider, Z., Cervenak, J., Baranyi, M., Papp, K., Prechl, J., Gloria, L., Erdei, A., and Kacskovics, I. (2011). Transgenic expression of bovine neonatal Fc receptor in mice boosts immune response and improves hybridoma production efficiency without any sign of autoimmunity. Immunology Letters. Jun 30; 137(1-2):62-9. PubMed
  13. Bender, B., Bodrogi, L., Mayer, B., Schneider, Z., Zhao, Y., Hammarstrom, L., Eggen, A., Kacskovics, I., and Bosze, Z. (2007). Position independent and copynumber- related expression of the bovine neonatal Fc receptor alpha-chain in transgenic mice carrying a 102 kb BAC genomic fragment. Transgenic Research 16, 613-627. PubMed